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Twinrix vaccine contains both recombinant proteins and killed virus.



Each Twinrix dose, for those 19 and over, contains 20 μg (micrograms) of purified hepatitis B surface antigen (HBsAg) protein and 720 ELISA units of inactivated hepatitis A viral antigen

(HM 175 strain) in 1 mL. (The Twinrix Junior dose has less)



There are no adjuvants and phenoxy ethanol is used in microscopic amounts as a preservative to prevent contamination.



Potential allergens include (things that could cause an allergic reaction...VERY RARE):

-neomycin

-trace amounts of thimerosal possible (most of it is removed in future production steps)

-latex (in stopper, pre-filled syringes)



Other materials include:

-yeast proteins

-polysorbate 20

-trace amounts of formaldehyde (which sounds scary, but humans actually have WAY more formaldehyde that we make ourselves circulating naturally in our bodies than can possibly be obtained from this vaccination)



Hope this helps